@@ 468,6 468,47 @@ frames} (ORFs) using ribosome profiling (ribo-seq) data. This package
provides the Ribotaper pipeline.")
(license license:gpl3+)))
+(define-public ribodiff
+ (package
+ (name "ribodiff")
+ (version "0.2.2")
+ (source
+ (origin
+ (method url-fetch)
+ (uri (string-append "https://github.com/ratschlab/RiboDiff/"
+ "archive/v" version ".tar.gz"))
+ (file-name (string-append name "-" version ".tar.gz"))
+ (sha256
+ (base32
+ "0wpbwmfv05wdjxv7ikm664f7s7p7cqr8jnw99zrda0q67rl50aaj"))))
+ (build-system python-build-system)
+ (arguments
+ `(#:python ,python-2
+ #:phases
+ (modify-phases %standard-phases
+ ;; Generate an installable executable script wrapper.
+ (add-after 'unpack 'patch-setup.py
+ (lambda _
+ (substitute* "setup.py"
+ (("^(.*)packages=.*" line prefix)
+ (string-append line "\n"
+ prefix "scripts=['scripts/TE.py'],\n")))
+ #t)))))
+ (inputs
+ `(("python-numpy" ,python2-numpy)
+ ("python-matplotlib" ,python2-matplotlib)
+ ("python-scipy" ,python2-scipy)
+ ("python-statsmodels" ,python2-statsmodels)))
+ (home-page "http://public.bmi.inf.ethz.ch/user/zhongy/RiboDiff/")
+ (synopsis "Detect translation efficiency changes from ribosome footprints")
+ (description "RiboDiff is a statistical tool that detects the protein
+translational efficiency change from Ribo-Seq (ribosome footprinting) and
+RNA-Seq data. It uses a generalized linear model to detect genes showing
+difference in translational profile taking mRNA abundance into account. It
+facilitates us to decipher the translational regulation that behave
+independently with transcriptional regulation.")
+ (license license:gpl3+)))
+
(define-public bioawk
(package
(name "bioawk")